Soybean oil (SBO) incorporated in situ polymerizable bioactive inorganic-organic hybrid resin containing alkoxide of zinc with polymerizable dimethacrylate groups (ZnSBOR) and soy protein concentrate (SPC)as filler along with surface treated quartz powder are used for the preparation of photopolymerized composite. ZnSBOR was synthesized using a modified sol-gel method. Soy flour without the oil was used as the SPC filler. Resin along with diluents, photoinitiator, activator/stabilizers and the filler components are mixed well in an agate mortar to get the uniform paste which upon exposure to visible light undergoes in situ polymerization to get cured composite. The photocured composite was evaluated in terms of linear polymerization shrinkage (LPS), depth of cure (DoC) and diametral tensile strength (DTS). The biocomposites (100QZNSBO) prepared using ZnSBOR showed significantly lower polymerization shrinkage and comparable diametral tensile strength (DTS) compared to composite prepared (100QZN) using ZnR. Good biological properties such as bioactivity and antimicrobial property of soybean merged with good physical properties will make the new Soybean oil (SBO) and soy protein concentrate (SPC) incorporated biocomposites as a suitable candidate material for biomedical applications.